At the turn of the fresh year , a squad of Italian scientists announced the find of two new cannabinoids found in marijuana . Although exactly what the compound do and how they pretend the human eubstance for the most part remain a mystery , the researcher say their findings add to our understanding of the “ controversial plant ” and foreground just how much remains to be discovered .
Tetrahydrocannabiphorol ( THCP ) has roughly the same structure as tetrahydrocannabinol ( THC ) – the main compound in marijuana responsible for its psychotropic properties – but is reportedly 30 times more potent than the well - known compound . In a pharmacologic examination , THCP “ hasten hypomotility , analgesia , catalepsy and decreased rectal temperature , ” suggesting it has a THC - same effect on the body . However , it is not yet clear whether THCP is psychoactive or if it produces the same “ pit ” effects as THC , although it looks like more active than THC at lower doses administered to mouse .
The researchers also isolate and identified cannabidiphorol ( CBDP ) , which is linked to CBD ( an antioxidant , anti - incendiary , anti - convulsant , and “ antagonist of THC negative effects ” ) .
To the best of their cognition , the author drop a line that a phytocannabinoid of such a structure ( with a “ linear alkyl side chain of mountains containing more than five carbon atoms ” ) has never been report as naturally occur . It could assist the scientific world to understand why dissimilar strains get unlike effects on the body , result in dissimilar feel , and advertise wellness and healing .
“ A routine of clinical trial and a uprise body of literature cater real evidence of the pharmacological potential of cannabis and cannabinoids on a across-the-board range of disorders from sleep to anxiousness , multiple induration , autism , and neuropathic hurting , ” write the authors inScientific Reports , adding that they ask THCP to be endowed with " an even higher tie chemical attraction for CB1 receptor [ in the brain ] and a greater cannabimimetic bodily process than THC itself . ”
Cannabis sativahas been found to have positive result on wellness way out like glaucoma and epilepsy , and provides an “ invaluable rootage of nutrient , ” while prove to be an environmentally well-disposed material for making fabric – it ’s also one of the most illicit drug in the human beings . Astoundingly , the plant is able to produce at least 150 constitutional molecules known as phytocannabinoids , most of which have never been isolated or characterise , with THC and CBD being the most well - know of the bunch . Until now , THC was the only one recognize to get a person high . THCP and CBDP levels were very lowly in the strains tested , but the researchers note that other breed of hemp may contain gamy traces of the compounds .
“ In our opinion , this chemical compound should be include in the inclination of the main phytocannabinoids to be set for a right evaluation of the pharmacological effect of the cannabis extracts administer to patient . In fact , we believe that the discovery of an extremely potent THC - like phytocannabinoid may shed light on several pharmacologic result not ascribable solely to THC , ” note the author .
The properties and potential uses of THCP and CBDP remain unsung – a determination that the authors reason out will expect further enquiry .
