Given the fact that it ’s ask for our nervous system to go decent and is lively for the output of rake , vitamin B12is pretty essential for our bodies . But while many believe that you could never have too much of a good matter , it seems that this is not the case here . According to unexampled research , an excess of this vitamin could prompt skin breakouts .
As described inScience Translational Medicine , researchers from theUniversity of California Los Angeles(UCLA ) found that vitamin B12 falsify the activities of a picky species of pelt bacteria that ’s link with acne , causing them to produce chemical compound that are known to trigger off inflammation in this skin disorder .
Although B12 is line up invarious foods – including meat , fish and eggs – at this stage there is insufficient grounds to intimate that changes in diet could help hoi polloi towards clear tegument . However , if further study support the suggested relationship between B12 and acne , people prostrate to the skin circumstance may want to reconsider vitamin subjoining choices as it is often found in high-pitched quantities in various multivitamin pill pills .
For the investigation , researcher were concerned in finding possible explanations for the observance that the vulgar pelt bacterium , Propionibacterium acnes , causes maculation in only a subset of individuals . They began by swab the faces of well-defined - skinned and pimple - ridden individual and culture the specie of interest . After comparing the two group , the researchers found that the biochemical pathway inP. acnesthat farm B12 was significantly dampened in those with acne .
To probe this possible relationship further , the skin germ were analyse in healthy , bit - free subjects that were give vitamin B12 injections . affirm the previous finding , they found that the bacterial B12 biosynthesis genes were repress follow supplement , almost mirror the expression patterns keep an eye on in those with acne . One patient even developed acne just one hebdomad after the injection .
For the terminal phase of their study , the squad culturedP. acnesin the science laboratory and exposed them to B12 , trust to find out more about the potential rudimentary mechanism for this apparent tie . They found that the vitamin increased the output of inflammatory compound called porphyrins , which have already been associated with the growth of acne .
Although this subject field ca n’t demonstrate that too much vitamin B12 causes acne , it does demonstrate that it is capable of altering gene expression in skin bacterium , which is interesting . Further studies will be involve before researchers are convinced of the linkup , particularly since some studies have found that B12 may act as an anti - inflammatory agent , which contradicts these findings , resilient Sciencepoints out .
[ ViaScience Translational Medicine , Live ScienceandThe Independent ]
